• Research Results

    The Department of Neurology at Lahey Hospital & Medical Center supports and participates in various original research efforts.  These efforts include investigator-initiated drug or device trials, observational studies, questionnaire studies, outcome studies, case reports and retrospective reviews. The results of these original projects are often published in peer reviewed journals or as book chapters. 

    2014 Publications

    Scott BJ, van Vugt VA, Rush T, et al. Concurrent intrathecal methotrexate and liposomal cytarabine for leptomeningeal metastasis from solid tumors: a retrospective cohort study. J Neurooncol. 2014 Sep;119(2):361-8. 

    Libon DJ, Penney DL, Davis R, et al. Deficits in Processing Speed and Decision Making in Relapsing-Remitting Multiple Sclerosis: The Digit Clock Drawing Test (dCDT). J Mult Scler. 2014;1(2):113. 

    Cohen J, Penney DL, Davis R, et al. Digital Clock Drawing: Differentiating Thinkingversus Doingin Younger and Older Adults with Depression. J Int Neuropsychol Soc. 2014 Oct;20(9):920-8. 

    Davis R, Libon DL, Au R, Putman D, Penney DL. THink: Inferring Cognitive Status from Subtle Behaviors. Association for the Advancement of Artificial Intelligence. 2014;2898-2905. 

    Kirschen M, Tsou A, Nelson SB, Russell JA, Larriviere D. Legal and ethical implications in the evaluation and management of sports-related concussion. Neurology. 2014;83:352–358. 

    Parres C, Thomas C, Ooi W, Bryan D, Ho D, Srinivasan J. Nontraumatic hypertrophic neuroma in treated Hansen disease. Neurology. 2014 Jan 7;82(1):93-4. 

    Karakis I, Vucic S, Srinivasan J. Facial Onset Sensory and Motor Neuronopathy (FOSMN) of Childhood Onset. Muscle and Nerve. 2014 Oct;50(4):614-5. 

    Barash JA, West JK, DeMaria A Jr. Accuracy of administrative diagnostic data for pathologically confirmed cases of Creutzfeldt-Jakob disease in Massachusetts, 2000-2008. Am J Infect Control. 2014 Jun;42(6):659-664. 

    Rosenthal MS, Barash J, Blackstock O, Ellis-West S, Filice C, Furie G, Greysen SR, Malone S, Tinney B, Yun K, Lucas GI. Building community capacity: sustaining the effects of multiple, two-year community-based participatory research projects. Prog Community Health Partnersh. 2014;8:365-374. 

     

    Past publications by Lahey Hospital & Medical Center neurology staff in 2013, 20122011 and 2010.

    Complete articles or abstracts may be available at http://www.ncbi.nlm.nih.gov/pubmed/.  

     

    Poster Presentations

    Poster Presentation, Doreen Ho, MD and Christopher Parres, MDPhysicians from the Department of Neurology also regularly present preliminary or final results of their original research in the format of poster presentations at peer reviewed neurological meetings often hosted by international professional associations or organizations, including the highly regarded annual meetings of the American Academy of Neurology and American Neurological Association.

     

    September 2014

    2014 Joint ACTRIMS-ECTRIMS Meeting 

    • Safety and Efficacy of Dimethyl Fumarate in Patients with Multiple Sclerosis - Real World Experience 

    June 2014 

    18th International Congress of Parkinson’s Disease and Movement Disorders   

    • Botox Use for Dystonia in Patients with Progressive Supranuclear Palsy 
    • Botox type and duration as a prognostic indicator in patients with PSP 
    • Effects of Coenzyme Q10 in PSP: A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study 
    • Dystonia gravidarum as the presenting clinical syndrome in a patient with the 8344A>G mitochondrial DNA MERRF mutation 

    May 2014

    2014 Annual Meeting of the Consortium of Multiple Sclerosis Centers (CMSC) 

    • Safety and Efficacy of Teriflunomide in Patients with Relapsing Remitting MS (RRMS) in a Community Setting
    • Safety and Efficacy of Dimethyl Fumarate in Patients with Relapsing Remitting MS (RRMS) in a Community Setting
    • Clinical characteristics and imaging features of Late Onset Multiple Sclerosis (LOMS)

    April 2014 

    66th Annual Meeting of the American Academy of Neurology (AAN) 

    •  CMT2A2 associated with novel mitofusion 2 double missense mutations 

     

    Clinical Trial Results 

    Clinical drug and device trials sponsored by pharamceutical and biotechnology companies are regularly conducted in the department of neurology at Lahey Hospital & Medical Center.  Once the results of these trials are finalized they are published in peer reviewed journals, and results may also be found on www.clinicaltrials.gov.

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  • Lahey Receives Stroke Award

    The American Heart Association/American Stroke Association's Get With The Guidelines program has again awarded Lahey Clinic’s stroke service the Stroke Gold Performance Achievement Award.