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Study
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Objective
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Contact
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A Multicenter, Observational, Open-Label, Single- Arm Study of Tysabri in Early Relapsing-Remitting Multiple Sclerosis in Anti-JCV Antibody Negative Patients
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Purpose: An observational study to determine which questionnaires and tests predict disease-free states for patients who are using Tysabri to treat early stages of Multiple Sclerosis.
For more information on this study, please visit: http://www.lahey.org/Departments_and_Locations/Departments/Neurology/Research/Multiple_Sclerosis_Trials.aspx
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Principal Investigator(s):
Claudia J. Chaves, MD
For more information about this Research Study call 781-744-8027.
Study Coordinator(s):
Rik Ganguly.
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A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy of Natalizumab on Reducing Disability Progression in Subjects with Secondary Progressive Multiple Sclerosis
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Purpose: To determine whether or not Tysabri is effective in reducing disability progression for Secondary Progressive Multiple Sclerosis (SPMS) patients as compared to Placebo.
For more information on this study, please visit: http://www.lahey.org/Departments_and_Locations/Departments/Neurology/Research/Multiple_Sclerosis_Trials.aspx
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Principal Investigator(s):
Ann Camac, MD
For more information about this Research Study call 781-744-8027.
Study Coordinator(s):
Rik Ganguly.
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Deep Brain Stimulation Surgery in the Subthalamic Nucleus for Parkinson's Disease Using Low Frequency Stimulation
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Purpose: The purpose of this study is to study the effectiveness of low frequency deep brain stimulation (DBS) or a combination of high/low frequency stimulation in patients with Parkinson’s disease (PD) who experience significant gait problems.
For more information on this study, please visit: http://www.lahey.org/Departments_and_Locations/Departments/Neurology/Research/Deep_Brain_Stimulation_Trials.aspx
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Principal Investigator(s):
Diana Apetauerova, MD
For more information about this Research Study call 781-744-8027.
Study Coordinator(s):
Nicholas F. Ventura,
Stephanie A. Scala, MA.
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Effects of Subthalamic Nucleus Stimulation on Striatal Dopaminergic Transmission in Patients with Parkinsons Disease
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Purpose: The effectiveness of DaTscan™ for monitoring disease progression or response to therapy, such as DBS, has not yet been established. We want to look at this dopamine activity with DaTscan before and after your DBS surgery to see if, what, changes occur in the brain.
For more information on this study, please visit: http://www.lahey.org/Departments_and_Locations/Departments/Neurology/Research/Deep_Brain_Stimulation_Trials.aspx
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Principal Investigator(s):
Diana Apetauerova, MD
For more information about this Research Study call 781-744-8027.
Study Coordinator(s):
Lynn A. Sullivan, MS,
Stephanie A. Scala, MA.
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Low-Frequency Repetitive Transcranial Magnetic Stimulation In Patients With Medication-Refractory Tardive Dyskinesia
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Purpose: The purpose of this study is to determine the safety, side effects and effectiveness of repetitive transcranial magnetic stimulation (rTMS) in tardive dyskinesia (TD). The effectiveness of rTMS will be tested by comparing it to the effects of sham rTMS (a procedure that mimics actual rTMS but does not deliver treatment).
For more information on this study, please visit: http://www.lahey.org/Departments_and_Locations/Departments/Neurology/Research/Tardive_Dyskinesia_Trials.aspx
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Principal Investigator(s):
Julie R. Leegwater-Kim, MD, PhD
For more information about this Research Study call 781-744-8027.
Study Coordinator(s):
Nicholas F. Ventura.
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Natural History of Benign Fasciculations
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Purpose: The purpose of this study is to further understand Benign Fasciculation Syndrome (BFS) and what factors may or may not possibly improve patient counseling and quality of life.
For more information on this study, please visit:
http://www.lahey.org/Departments_and_Locations/Departments/Neurology/Research/Benign_Fasciculation_Syndrome_Trials.aspx
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Principal Investigator(s):
Doreen T. Ho, MD
For more information about this Research Study call 781-744-8027.
Study Coordinator(s):
Lynn A. Sullivan, MS.
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Open Label Trial Of 3,4-Diaminopyridine In Lambert-Eaton Myasthenic Syndrome (LEMS) and Congenital Myasthenic Syndromes (CMS)
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Purpose: This study is looking at the effectiveness and adverse effects of 3, 4 Diaminopyridine (3, 4 DAP) for the treatment of Lambert-Eaton Myasthenic Syndrome (LEMS) and Congenital Myasthenic Syndromes (CMS).
For more information on this study, please visit: http://www.lahey.org/Departments_and_Locations/Departments/Neurology/Research/Lambert_Eaton_Myasthenic_Syndrome_Trials.aspx
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Principal Investigator(s):
Jayashri Srinivasan, MD, PhD, FRCP
For more information about this Research Study call 781-744-8027.
Study Coordinator(s):
Nicholas F. Ventura.
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