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We are currently planning a study on the use of deep brain stimulation in the treatment of obsessive-compulsive disorder (OCD), severe refractory depression and possibly drug and alcohol addiction. While this work is exciting, it is also very experimental and we are proceeding with caution. To date, a few encouraging reports have shown that the use of DBS for these problems may be very effective. We have both the resources and skills to provide this option for selected patients in these studies.