OXA-type ß-Lactamases
«« Back
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Enzyme
|
Nucleotide
|
pI
|
Reference
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OXA-1
|
J02967
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7.4
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PNAS 84:7378, 1987
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OXA-2
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X07260
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7.7
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Eur. J. Biochem. 180:309, 1989
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OXA-3
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L07945
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7.1
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AAC 39:887, 1995
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OXA-4
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AY162283
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7.5
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AAC 39:887, 1995
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OXA-5
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X58272
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7.6
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Mol Microbiol. 6:1693, 1992
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OXA-6
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7.7
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OXA-7
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X75562
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7.7
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AAC 39:1379, 1995
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OXA-8
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OXA-9
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M55547
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6.9
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Plasmid 29:31, 1993
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OXA-10
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U37105
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6.1
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AAC 32:134, 1988
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OXA-11
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Z22590
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6.4
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AAC 37:1637, 1993
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OXA-12
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U10251
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8.6
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AAC 38:2078, 1994
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OXA-13
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U59183
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8
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Microbiology 144:1021, 1998
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OXA-14
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L38523
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6.2
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AAC39:1881, 1995
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OXA-15
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U63835
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8.7
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AAC41:785, 1997
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OXA-16
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AF043100
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6.2
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AAC42:3117, 1998
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OXA-17
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AF060206
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6.1
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AAC43:1362, 1999
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OXA-18
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U85514
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5.5
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AAC41:2188, 1997
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OXA-19
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AF043381
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7.6
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AAC42:3113, 1998
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OXA-20
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AF024602
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7.4
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AAC42:2074, 1998
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OXA-21
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Y10693
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7
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AAC41:2757, 1997
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OXA-22
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AFO64820
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7
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AAC44:2201, 2000
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OXA-23
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AJ132105
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6.7
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AAC44:196, 2000
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OXA-24
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AJ239129
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9
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AAC44:1556, 2000
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OXA-25
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AF201826
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8
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AAC45:583, 2001
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OXA-26
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AF201827
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7.9
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AAC45:583, 2001
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OXA-27
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AF201828
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6.8
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AAC45:583, 2001
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OXA-28
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AF231133
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8.1
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AAC45:447, 2001
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OXA-29
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AJ400619
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>=9.0
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AAC45:3509, 2001
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OXA-30*
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AF255921
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7.3
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AAC44:2034, 2000
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OXA-31
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AF294653
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7.5
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AAC45:1615, 2001
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OXA-32
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AF315351
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7.7
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AAC46:566, 2002
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OXA-33
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AY008291
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OXA-34
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AF350424
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OXA-35
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AF315786
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8
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JAC48:717, 2001
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OXA-36
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AF300985
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OXA-37
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AY007784
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7.4
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Microb. Drug Res. 8:261, 2002
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OXA-38
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Assigned
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OXA-39
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Assigned
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OXA-40
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AF509241
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8.6
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J. Clin. Micro. 40:4741-4743, 2002
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OXA-41
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Assigned
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OXA-42
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AJ488302
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JAC 50: 445, 2002
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OXA-43
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AJ488303
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JAC 50: 445, 2002
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OXA-44
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Assigned
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OXA-45
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AJ519683
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AAC 47:2859,2003
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OXA-46
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AF317511
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AAC 49:1973, 2005
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OXA-47
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AY237830
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AAC48:15, 2004
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OXA-48
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AY236073
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AAC 48:15, 2004
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OXA-49
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AY288523
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OXA-50
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AY306130
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AAC 48:2043, 2004
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OXA-51
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AJ309734
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Clin. Microbiol. Infect.11:15-23, 2005
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OXA-52
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Assigned
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OXA-53
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AY289608
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JAC 54:354, 2004
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OXA-54
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AY500137
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AAC 48:348, 2004
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OXA-55
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AY343493
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AAC 48:1670, 2004
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OXA-56
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AY445080
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AAC 48:1406, 2004
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OXA-57
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AJ631966
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AAC 49:1639, 2005
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OXA-58
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AY570763
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AAC 49:202, 2005
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OXA-59
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AJ632249
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AAC 49:1639, 2005
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OXA-60
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AF525303
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5.1
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AAC 48:4217, 2004
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OXA-61
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AY587956
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AAC 49: 2515, 2005
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OXA-62
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AY423074
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AAC 50:1330, 2006
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OXA-63
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AY619003
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AAC 52:1264, 2008
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OXA-64
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AY750907
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Clin. Microbiol. Infect. 11: 326, 2005
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OXA-65
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AY750908
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Clin. Microbiol. Infect. 11: 326, 2005
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OXA-66
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AY750909
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Clin. Microbiol. Infect. 11: 326, 2005
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OXA-67
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DQ491200
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OXA-68
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AY750910
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Clin. Microbiol. Infect. 11: 326, 2005
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OXA-69
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AY750911
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Clin. Microbiol. Infect. 11: 326, 2005
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OXA-70
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AY750912
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Clin. Microbiol. Infect. 11: 326, 2005
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OXA-71
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AY750913
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Clin. Microbiol. Infect. 11: 326, 2005
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OXA-72
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EF534256
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AAC 51: 4022-4028, 2007
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OXA-73
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AY762325
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OXA-74
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AJ854182
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JCM 45:2829-2834, 2007
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OXA-75
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AY859529
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AAC49:4174,2005
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OXA-76
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AY949203
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AAC 49: 4174, 2005
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OXA-77
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AY949202
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AAC 49: 4174, 2005
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OXA-78
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AY862132
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OXA-79
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EU019534
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Clin. Microbiol. Infect. 13:1137-1138, 2007
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OXA-80
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EU019535
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Clin. Microbiol. Infect. 13:1137-1138, 2007
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OXA-81
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Assigned
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OXA-82
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EU019536
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Clin. Microbiol. Infect. 13:1137-1138, 2007
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OXA-83
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DQ309277
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FEMS Microbiol. Lett. 258:72, 2006
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OXA-84
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DQ309276
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FEMS Microbiol. Lett. 258:72, 2006
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OXA-85
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AY227054
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AAC 50:2673, 2006
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OXA-86
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DQ149247
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JAC 58: 537-542, 2006.
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OXA-87
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DQ348075
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JAC 58: 537-542, 2006.
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OXA-88
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DQ392963
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JAC 59: 627-632, 2007
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OXA-89
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DQ445683
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Int. J. Antimicrob Agents 28:110, 2006
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OXA-90
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AM231719
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OXA-91
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DQ519083
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JAC 59: 627-632, 2007
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OXA-92
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DQ335566
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Clin. Microbiol. Infect. 13: 348-349, 2007
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OXA-93
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DQ519087
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JAC 59: 627-632, 2007
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OXA-94
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DQ519088
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JAC 59: 627-632, 2007
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OXA-95
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DQ519089
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JAC 59: 627-632, 2007
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OXA-96
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DQ519090
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JAC 59: 627-632, 2007
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OXA-97
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EF102240
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AAC 52:1613-1617, 2008
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OXA-98
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AM279652
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OXA-99
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DQ888718
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Int. J. Antimicrob. Agents 34:285-286, 2009
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OXA-100
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Assigned
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OXA-101
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AM412777
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OXA-102
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Assigned
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OXA-103
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Assigned
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OXA-104
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EF581285
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Clin. Microbiol. Infect. 13:1137-1138, 2007
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OXA-105
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Assigned
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OXA-106
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EF650032
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Clin. Microbiol. Infect. 13:1137-1138, 2007
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OXA-107
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EF650033
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Clin. Microbiol. Infect. 13:1137-1138, 2007
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OXA-108
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EF650034
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Clin. Microbiol. Infect. 13:1137-1138, 2007
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OXA-109
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EF650035
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Clin. Microbiol. Infect. 13:1137-1138, 2007
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OXA-110
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EF650036
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Clin. Microbiol. Infect. 13:1137-1138, 2007
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OXA-111
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EF650037
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Clin. Microbiol. Infect. 13:1137-1138, 2007
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OXA-112
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EF650038
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Clin. Microbiol. Infect. 13:1137-1138, 2007
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OXA-113
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EF653400
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JAC 60:1174-1176, 2007
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OXA-114a
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EU188842
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AAC 52:1952-1956, 2008
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OXA-115
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EU029998
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OXA-116
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EU220744
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OXA-117
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EU220745
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OXA-118
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AF371964
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J. Appl. Microbiol. 92:992-1004, 2002
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OXA-119
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AY139598
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FEMS Microbiol. Ecol. 45:239-252, 2003
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OXA-120
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Assigned
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OXA-121
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Assigned
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OXA-122
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Assigned
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OXA-123
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Assigned
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OXA-124
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Assigned
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OXA-125
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Assigned
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OXA-126
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Assigned
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OXA-127
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Assigned
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OXA-128
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EU375515
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JAC 63:828-830, 2009
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OXA-129
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AM932669
|
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Int. J. Antimicrob. Agents 32:120-129, 2008
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OXA-130
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EU547445
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J. Chemother. 21: 290-295, 2009
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OXA-131
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EU547446
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J. Chemother. 21: 290-295, 2009
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OXA-132
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EU547447
|
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J. Chemother. 21: 290-295, 2009
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OXA-133
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EU571228
|
|
AAC 53:843-844, 2009
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OXA-134
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Assigned
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OXA-135
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|
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Assigned
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OXA-136
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EU086830
|
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J. Med. Microbiol. 57: 1122-1128, 2008
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OXA-137
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EU086834
|
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J. Med. Microbiol. 57: 1122-1128, 2008
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OXA-138
|
EU670845
|
|
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OXA-139
|
|
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Assigned
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OXA-140
|
|
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Assigned
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OXA-141
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EF552405
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|
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OXA-142
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EU358785
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|
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OXA-143
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GQ861437
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OXA-144
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Assigned
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OXA-145
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FJ790516
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|
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OXA-146
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FJ194494
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OXA-147
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FJ848783
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|
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OXA-148
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GQ853679
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|
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OXA-149
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GQ853680
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|
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OXA-150
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GQ853681
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|
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OXA-151
|
|
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Assigned
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OXA-152
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|
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Assigned
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OXA-153
|
|
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Assigned
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OXA-154
|
|
|
Assigned
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OXA-155
|
|
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Assigned
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OXA-156
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|
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Assigned
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OXA-157
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|
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Assigned
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OXA-158
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|
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Assigned
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OXA-159
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|
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Assigned
|
*Note: the corrected sequence for OXA-1 is identical to that of OXA-30. The amino acid sequences of OXA-4 and OXA-35, of OXA-24 and OXA-40, and of OXA-46 and OXA-81 are also indistinguishable.
CTX-M-type ß-Lactamases
|
ß-Lactamase
|
Nucleotide
|
Reference
|
|
CTX-M-1
|
X92506
|
AAC40:509, 1996
|
|
CTX-M-2
|
X92507
|
AAC40:509, 1996
|
|
CTX-M-3
|
Y10278
|
AAC42:827, 1998
|
|
CTX-M-4
|
Y14156
|
AAC42:1259, 1998
|
|
CTX-M-5
|
U95364
|
AAC42:1980, 1998
|
|
CTX-M-6
|
AJ005044
|
FEMS Micro Lett. 165:289, 1998
|
|
CTX-M-7
|
AJ005045
|
FEMS Micro Lett. 165:289, 1998
|
|
CTX-M-8
|
AF189721
|
AAC44:1936, 2000
|
|
CTX-M-9
|
AF174129
|
AAC44:1970, 2000
|
|
CTX-M-10
|
AF255298
|
AAC45:616, 2001
|
|
CTX-M-11
|
AY005110
|
|
|
CTX-M-12
|
AF305837
|
AAC45:2141, 2001
|
|
CTX-M-13
|
AF252623
|
AAC 46:630, 2002
|
|
CTX-M-14
|
AF252622
|
AAC 46:630, 2002
|
|
CTX-M-15 (UOE-1)
|
AY044436
|
FEMS Microbiol. Lett. 201:237, 2001
|
|
CTX-M-16
|
AY029068
|
AAC 45:2269, 2001
|
|
CTX-M-17
|
AY033516
|
AAC 46:1212, 2002
|
|
CTX-M-18
|
AF325133
|
AAC 45:3355, 2001
|
|
CTX-M-19
|
AF325134
|
AAC 45:3355, 2001
|
|
CTX-M-20
|
AJ416344
|
FEMS Microbiol. Lett. 209:161, 2002
|
|
CTX-M-21
|
AJ416346
|
FEMS Microbiol. Lett. 209:161, 2002
|
|
CTX-M-22
|
AY080894
|
J. Infect. 54:53, 2007
|
|
CTX-M-23
|
AF488377
|
JAC 54:406, 2004
|
|
CTX-M-24
|
AY143430
|
JAC 57:14-23, 2006
|
|
CTX-M-25
|
AF518567
|
AAC 48:4829, 2004
|
|
CTX-M-26
|
AY157676
|
JAC 51:195, 2003
|
|
CTX-M-27
|
AY156923
|
JAC 52:29, 2003
|
|
CTX-M-28
|
AJ549244
|
JAC 56:115-121, 2005
|
|
CTX-M-29
|
AY267213
|
J. Infect. 54:53, 2007
|
|
CTX-M-30
|
AY292654
|
AAC 48:4435, 2004
|
|
CTX-M-31
|
AJ567481
|
AAC 47:2864, 2003
|
|
CTX-M-32
|
AJ557142
|
AAC 48:2308, 2004
|
|
CTX-M-33
|
AY238472
|
Int. J. Antimicrob. Agents 29: 598-600, 2007
|
|
CTX-M-34
|
AY515297
|
JAC 56:1152, 2005
|
|
CTX-M-35
|
Assigned
|
|
|
CTX-M-36
|
AB177384
|
|
|
CTX-M-37
|
AY649755
|
Int. J. Antimicrob. Agents 28:288-291, 2006
|
|
CTX-M-38
|
AY822595
|
Chin. J. Infect. Chemother. 9:216-218, 2009
|
|
CTX-M-39
|
AY954516
|
AAC49:4745,2005
|
|
CTX-M-40
|
AY750914
|
Int. J. Antimicrob. Agents 27:572, 2006
|
|
CTX-M-41
|
DQ023162
|
JAC 62:289-295, 2008
|
|
CTX-M-42
|
DQ061159
|
AAC 52:1297-1301, 2008
|
|
CTX-M-43
|
DQ102702
|
JAC 57:975, 2006
|
|
CTX-M-44 (Toho-1)
|
D37830
|
AAC 39: 269, 1995
|
|
CTX-M-45 (Toho-2)
|
D89862
|
AAC 42: 1181, 1998
|
|
CTX-M-46
|
AY847147
|
JCM 43:4301, 2005
|
|
CTX-M-47
|
AY847143
|
JCM 43: 4301, 2005 (renumbered)
|
|
CTX-M-48
|
AY847144
|
JCM 43: 4301, 2005 (renumbered)
|
|
CTX-M-49
|
AY847145
|
JCM 43: 4301, 2005 (renumbered)
|
|
CTX-M-50
|
AY847146
|
JCM 43: 4301, 2005 (renumbered)
|
|
CTX-M-51
|
DQ211987
|
|
|
CTX-M-52
|
DQ223685
|
|
|
CTX-M-53
|
DQ268764
|
AAC 53: 1944-1951, 2009
|
|
CTX-M-54
|
DQ303459
|
JAC 58:315, 2006
|
|
CTX-M-55
|
DQ885477
|
Diag. Microbiol. Infect Dis. 58:349, 2007
|
|
CTX-M-56
|
EF374097
|
AAC 51:2720-2725, 2007
|
|
CTX-M-57
|
DQ810789
|
Int. J. Antimicrob. Agents 31:85-86, 2008
|
|
CTX-M-58
|
EF210159
|
|
|
CTX-M-59
|
DQ408762
|
AAC 52:1790-1793, 2008
|
|
CTX-M-60
|
AM411407
|
|
|
CTX-M-61
|
EF219142
|
JAC 60:956-964, 2007
|
|
CTX-M-62
|
EF219134
|
AAC 52:4198-4202, 2008
|
|
CTX-M-63
|
AB205197
|
|
|
CTX-M-64
|
AB284167
|
AAC 53: 69-74, 2009
|
|
CTX-M-65
|
EF418608
|
AAC 52:1204-1205, 2008
|
|
CTX-M-66
|
EF576988
|
Diag. Microbiol Inf. Dis. 60:169-175, 2008
|
|
CTX-M-67
|
EF581888
|
Int. J. Antimicrob. Agents 32: 534-537, 2008
|
|
CTX-M-68
|
EU177100
|
Int. J. Antimicrob. Agents 34: 544-549, 2009
|
|
CTX-M-69
|
EU402393
|
|
|
CTX-M-70
|
Assigned
|
|
|
CTX-M-71
|
FJ815436
|
AAC 53: 4518-4521, 2009
|
|
CTX-M-72
|
AY847148
|
J. Gen. Appl. Microbiol. 55: 207-216, 2009
|
|
CTX-M-73
|
Assigned
|
|
|
CTX-M-74
|
GQ149243
|
Diagn. Microbiol. Infect. Dis. 65: 202-206, 2009
|
|
CTX-M-75
|
GQ149244
|
Diagn. Microbiol. Infect. Dis. 65: 202-206, 2009
|
|
CTX-M-76
|
AM982520
|
|
|
CTX-M-77
|
AM982521
|
|
|
CTX-M-78
|
AM982522
|
|
|
CTX-M-79
|
EF426798
|
Can. J. Microbiol. 54: 781-785, 2008
|
|
CTX-M-80
|
EU202673
|
|
|
CTX-M-81
|
EU136031
|
|
|
CTX-M-82
|
DQ256091
|
JAC 63:895-900, 2009
|
|
CTX-M-83
|
FJ214366
|
JAC 63:87-94, 2009
|
|
CTX-M-84
|
FJ214367
|
JAC 63:87-94, 2009
|
|
CTX-M-85
|
FJ214368
|
JAC 63:87-94, 2009
|
|
CTX-M-86
|
FJ214369
|
JAC 63:87-94, 2009
|
|
CTX-M-87
|
EU545409
|
J. Med. Microbiol. 58: 811-815, 2009
|
|
CTX-M-88
|
FJ873739
|
|
|
CTX-M-89
|
FJ971899
|
JCM 47:2970-2974, 2009
|
|
CTX-M-90
|
FJ907381
|
|
|
CTX-M-91
|
GQ870432
|
|
|
CTX-M-92
|
GU127598
|
|
Note: the amino acid sequences of CTX-M-14 and CTX-M-18 and of CTX-M-55 and CTX-M-57 are identical.
CMY-type ß-Lactamases
|
Enzyme
|
Nucleotide
|
Reference
|
|
CMY-1
|
X92508
|
AAC 40:1926-1930, 1996
|
|
CMY-2
|
X91840
|
AAC 40: 221-224, 1996
|
|
CMY-3
|
Y16783
|
AAC 42: 1110-1114, 1998
|
|
CMY-4
|
Y15130
|
FEMS Microbiol Lett. 169:235-240, 1998
|
|
CMY-5
|
Y17716
|
AAC 43: 1350-1357, 1999
|
|
CMY-6
|
AJ011293
|
|
|
CMY-7
|
AJ011291
|
JAC 49:1011-1014, 2002
|
|
CMY-8
|
AF167990
|
AAC 44: 1438-1442, 2000
|
|
CMY-9
|
AB061794
|
AAC 46: 2427-2434, 2002
|
|
CMY-10
|
AF357597
|
J. Appl. Microbiol. 95:744, 2003
|
|
CMY-11
|
AF357599
|
JAC 49:269-273, 2002
|
|
CMY-12
|
Y16785
|
JAC 50:681-688, 2002
|
|
CMY-13
|
AY339625
|
AAC 48:3172, 2004
|
|
CMY-14
|
AJ555825
|
AAC 48:4136-4143, 2004.
|
|
CMY-15
|
AJ555823
|
AAC 48:4136-4143, 2004
|
|
CMY-16
|
AJ781421
|
AAC 50: 618-624, 2006
|
|
CMY-17
|
AY513266
|
|
|
CMY-18
|
AY743434
|
Microbial Drug Resistance 12:44-49, 2006
|
|
CMY-19
|
AB194410
|
AAC 50: 534-541, 2006
|
|
CMY-20
|
AY960293
|
Diagn. Microbiol. Infect. Dis. 60:405-408, 2008
|
|
CMY-21
|
DQ139328
|
Int J Antimicrob Agents 28: 80-2, 2006
|
|
CMY-22
|
DQ256079
|
|
|
CMY-23
|
DQ463751
|
JAC 59: 102-5, 2007
|
|
CMY-24
|
EF415650
|
Int. J. Antimicrob. Agents 30:278-280, 2007
|
|
CMY-25
|
EU515249
|
|
|
CMY-26
|
AB300358
|
Appl Environ Microbiol 73:6686. 2007
|
|
CMY-27
|
EU515250
|
|
|
CMY-28
|
EF561644
|
|
|
CMY-29
|
EF685371
|
AAC 53: 3178, 2009
|
|
CMY-30
|
EF685372
|
AAC 53: 3178, 2009
|
|
CMY-31
|
EF622224
|
JAC 61:457-458, 2008
|
|
CMY-32
|
EU496815
|
|
|
CMY-33
|
EU496816
|
|
|
CMY-34
|
EF394370
|
|
|
CMY-35
|
EF394371
|
|
|
CMY-36
|
EU331426
|
AAC 53:1256-1259,2009
|
|
CMY-37
|
AB280919
|
Int. J. Antimicrob. Agents 32:256-261, 2008
|
|
CMY-38
|
AM931008
|
AAC 52:2449-2454, 2008
|
|
CMY-39
|
AB372224
|
|
|
CMY-40
|
EU515251
|
|
|
CMY-41
|
AB429270
|
J. Food Prot. 72: 624-630, 2009
|
|
CMY-42
|
Assigned
|
|
|
CMY-43
|
FJ360626
|
|
|
CMY-44
|
FJ437066
|
|
|
CMY-45
|
Assigned
|
|
|
CMY-46
|
Assigned
|
|
Other AmpC-type ß-Lactamases
|
Name
|
Nucleotide
|
Reference
|
|
ACC-1
|
AJ133121
|
AAC 43:1924-1931, 1999
|
|
ACC-2
|
AF180952
|
AAC 44:1470-1478, 2000
|
|
ACC-3
|
AF180958
|
AAC 44:1470-1478, 2000
|
|
ACC-4
|
EF504260
|
AAC 51:3763-3767, 2007
|
|
|
|
|
|
ACT-1
|
U58495
|
AAC 41:563-569, 1997
|
|
ACT-2
|
AM076977
|
|
|
ACT-3
|
EF125013
|
Int. J. Antimicrob. Agents 33:95-96, 2009
|
|
ACT-4
|
EU427302
|
|
|
ACT-5
|
FJ237369
|
|
|
ACT-6
|
FJ237366
|
|
|
ACT-7
|
FJ237368
|
|
|
|
|
|
|
CFE-1
|
AB107899
|
AAC 48:1151-1158, 2004
|
|
|
|
|
|
DHA-1
|
Y16410
|
AAC 42:2352-2358, 1998
|
|
DHA-2
|
AF259520
|
JAC 47:207-210, 2001
|
|
|
|
|
|
FOX-1
|
X77455
|
AAC 38:2150-2157, 1994
|
|
FOX-2
|
Y10282
|
AAC 41:2041-2046, 1997
|
|
FOX-3
|
Y11068
|
AAC 42:464-467, 1998
|
|
FOX-4
|
AJ277535
|
AAC 44:2549-2553, 2000
|
|
FOX-5
|
AY007369
|
AAC 45:3189-3194, 2001
|
|
FOX-6
|
AY034848
|
identical to FOX-5
|
|
FOX-7
|
AJ703795
|
|
|
|
|
|
|
LAT-1
|
X78117
|
AAC 38:2207-2209, 1994
|
|
|
|
|
|
MIR-1
|
M37839
|
AAC 34:2200-2209, 1990
|
|
MIR-2
|
AY227752
|
|
|
MIR-3
|
AY743435
|
|
|
MIR-4
|
EF417572
|
Curr. Microbiol. 57:558-563, 2008
|
|
MIR-5
|
FJ237367
|
|
|
|
|
|
|
MOX-1
|
D13304
|
Gene 139:93-98, 1994
|
|
MOX-2
|
AJ276453
|
AAC 46:2262-2265, 2002
|
|
MOX-3
|
EU515248
|
|
|
MOX-4
|
FJ262599
|
|
|
MOX-5
|
GQ152600
|
|
|
MOX-6
|
GQ152601
|
|
|
MOX-7
|
GQ152602
|
|
On resequencing BIL-1 and LAT-2 proved identical to CMY-2, LAT-3 was identical to CMY-6, and LAT-4 was identical to LAT-1 (AAC 46:1190-1198, 2002).
IMP-type ß-Lactamases
|
Enzyme
|
Nucleotide
|
Reference
|
|
IMP-1
|
S71932
|
AAC 38:71-78, 1994
|
|
IMP-2
|
AJ243491
|
AAC 44:1229-1235, 2000
|
|
IMP-3
|
AB010417
|
AAC 44:2023-2027, 2000
|
|
IMP-4
|
AF244145
|
AAC 45:710-714, 2001
|
|
IMP-5
|
AF290912
|
FEMS Microbiol. Lett. 215: 33-39, 2002.
|
|
IMP-6
|
AB040994
|
AAC 45:1343-1348, 2001
|
|
IMP-7
|
AF318077
|
AAC 46:255-258, 2002
|
|
IMP-8
|
AF322577
|
AAC 45: 2368-2371, 2001
|
|
IMP-9
|
AY033653
|
AAC 50:355-358, 2006
|
|
IMP-10
|
AB074433
|
AAC 46:2014-2016, 2002
|
|
IMP-11
|
AB074436
|
|
|
IMP-12
|
AJ420864
|
AAC 47:1522-1528, 2003
|
|
IMP-13
|
AJ550807
|
JAC 52:583, 2003
|
|
IMP-14
|
AY553332
|
|
|
IMP-15
|
AY553333
|
AAC 52:2289-2290, 2008
|
|
IMP-16
|
AJ584652
|
AAC 48:4693, 2004
|
|
IMP-17
|
Assigned
|
|
|
IMP-18
|
AY780674
|
AAC 50:2272-2273, 2006
|
|
IMP-19
|
EF118171
|
AAC 51:4486-4488, 2007
|
|
IMP-20
|
AB196988
|
|
|
IMP-21
|
AB204557
|
|
|
IMP-22
|
DQ361087
|
JAC 63:901-908, 2009
|
|
IMP-23
|
Assigned
|
|
|
IMP-24
|
EF192154
|
Int. J. Antimicrob. Agents 32: 475-480, 2008.
|
|
IMP-25
|
EU541448
|
|
|
IMP-26
|
Assigned
|
|
IND-type ß-lactamases
|
Enzyme
|
Nucleotide
|
Reference
|
|
IND-1
|
AF099139
|
FEMS Microbiol. Lett. 171:127, 1999
|
|
IND-2
|
AF219127
|
AAC 44:3028, 2000
|
|
IND-2a
|
AF219130
|
AAC 44:3028, 2000
|
|
IND-3
|
AF219131
|
AAC 44:3028, 2000
|
|
IND-4
|
AF219135
|
AAC 44:3028, 2000
|
|
IND-5
|
AY504627
|
AAC 51:2988, 2007
|
|
IND-6
|
AM087455
|
AAC 53:4320, 2009
|
|
IND-7
|
Assigned
|
|
VIM-type ß-Lactamases
|
Enzyme
|
Nucleotide
|
Reference
|
|
VIM-1
|
Y18050
|
AAC 43: 1584, 1999
|
|
VIM-2
|
AF191564
|
AAC 44: 891, 2000
|
|
VIM-3
|
AF300454
|
AAC 45: 2224, 2001
|
|
VIM-4
|
AY135661
|
AAC 46: 4026, 2002
|
|
VIM-5
|
AY144612
|
JAC 54:282, 2004
|
|
VIM-6
|
AY165025
|
AAC 48:2334, 2004
|
|
VIM-7
|
AJ536835
|
AAC48:329, 2004
|
|
VIM-8
|
AY524987
|
JCM 42:5094-5101, 2004
|
|
VIM-9
|
AY524988
|
|
|
VIM-10
|
AY524989
|
|
|
VIM-11
|
AY605049
|
AAC 49:474-5, 2005.
|
|
VIM-12
|
DQ143913
|
AAC 49:5153-5156, 2005
|
|
VIM-13
|
DQ365886
|
AAC 52:3589-3596, 2008
|
|
VIM-14
|
AY635904
|
|
|
VIM-15
|
EU419745
|
AAC 52:2977-2979, 2008
|
|
VIM-16
|
EU419746
|
AAC 52:2977-2979, 2008
|
|
VIM-17
|
EU118148
|
AAC 53:1325-1330, 2009
|
|
VIM-18
|
AM778091
|
AAC 53:1225-1227, 2009
|
|
VIM-19
|
Assigned
|
|
|
VIM-20
|
Assigned
|
|
|
VIM-21
|
Assigned
|
|
|
VIM-22
|
Assigned
|
|
|
VIM-23
|
GQ242167
|
|
KPC-type ß-Lactamases
|
Enzyme
|
Nucleotide
|
Reference
|
|
KPC-1
|
AF297554
|
AAC 45:1151,2001
|
|
KPC-2
|
AY034847
|
JAC 51:711, 2003
|
|
KPC-3
|
AF395881
|
AAC 48:4793-4799, 2004
|
|
KPC-4
|
AY700571
|
AAC 53:557-562, 2009
|
|
KPC-5
|
EU400222
|
AAC 53:557-562, 2009
|
|
KPC-6
|
EU555534
|
|
|
KPC-7
|
EU729727
|
|
|
KPC-8
|
FJ234412
|
|
|
KPC-9
|
FJ624872
|
|
|
KPC-10
|
GQ140348
|
|
Note: The revised sequence of "KPC-1" is identical to that of KPC-2 and consequently KPC-1 is no longer a valid designation (AAC 52:809, 2008).
GES-type ß-Lactamases
Revised numbering per AAC 49:2148,2005 and J. Microbiol. Biotechnol. 16: 1837-1840, 2006.
|
Enzyme
|
Nucleotide
|
Reference
|
|
GES-1
|
AF156486
|
AAC 44: 622, 2000
|
|
GES-2
|
AF326355
|
AAC 45: 2598, 2001
|
|
GES-3
|
AB113580
|
AAC 48: 1960, 2004
|
|
GES-4
|
AB116260
|
AAC 48: 2905, 2004
|
|
GES-5
|
AY494717
|
FEMS Microbiol. Lett. 234: 209, 2004
|
|
GES-6
|
AY494718
|
FEMS Microbiol. Lett. 234: 209, 2004
|
|
GES-7 (IBC-1)
|
AF208529
|
AAC 44: 2247, 2000
|
|
GES-8 (IBC-2)
|
AF329699
|
JAC 48: 627, 2001
|
|
GES-9
|
AY920928
|
AAC 49: 3593, 2005
|
|
GES-10
|
Assigned
|
|
|
GES-11
|
FJ854362
|
AAC 53: 3579-3581, 2009
|
|
GES-12
|
FN554543
|
|
|
GES-13
|
Assigned
|
|
PER-type ß-Lactamases
|
Enzyme
|
Nucleotide
|
Reference
|
|
PER-1
|
Z21957
|
AAC 38: 104, 1994
|
|
PER-2
|
X93314
|
AAC 40: 616,1996
|
|
PER-3
|
AY740681
|
|
|
PER-4
|
EU748544
|
|
|
PER-5
|
EU687473
|
Diagn. Microbiol. Infect. Dis. 64:389-395, 2009
|
|
PER-6
|
Assigned
|
|
VEB-type ß-Lactamases
|
Enzyme
|
Nucleotide
|
Reference
|
|
VEB-1
|
AF010416
|
AAC 43: 573, 1999
|
|
VEB-2
|
AY027870
|
Clin. Infect. Dis. 34: 603, 2002
|
|
VEB-3
|
AY536519
|
JCM 43: 826, 2005
|
|
VEB-4
|
EF136375
|
JAC 61: 1029-1032, 2008
|
|
VEB-5
|
EF420108
|
|
|
VEB-6
|
EU259884
|
AAC 52: 794-795, 2008
|
|
VEB-7
|
FJ825622
|
|
SME-type ß-Lactamases
|
Enzyme
|
Nucleotide
|
Reference
|
|
SME-1
|
Z28968
|
AAC 38: 1262, 1994
|
|
SME-2
|
AF275256
|
AAC 44: 3035, 2000
|
|
SME-3
|
AY584237
|
AAC 50: 3485, 2006
|
Isoelectric points of potentially plasmid-mediated ESBLs not conferring resistance to cephamycins (pIs have not been reported for all ESBLs)
|
|
|
|
5.2
|
TEM-55 TEM-57 TEM-58 TEM-70 TEM-122 TEM-125
|
|
5.3
|
TEM-12 TEM-25 PER-1
|
|
5.4
|
TEM-7 TEM-19 TEM-20 TEM-29 TEM-112 TEM-126
|
|
5.5
|
TEM-9 TEM-17 OXA-18
|
|
5.6
|
TEM-5 TEM-10 TEM-11 TEM-13 TEM-26 TEM-50 TEM-59 TEM-63
|
|
5.7
|
TEM-68
|
|
5.8
|
TEM-42 GES-1 GES-2 IBC-2
|
|
5.9
|
TEM-4 TEM-6 TEM-8 TEM-27 TEM-69 TEM-72 TEM-114
|
|
6
|
TEM-15 TEM-47 TEM-48 TEM-49 TEM-52 TEM-66 TEM-109
|
|
6.1
|
TEM-28 TEM-43 OXA-17
|
|
6.2
|
OXA-14 OXA-16
|
|
6.3
|
TEM-3 TEM-16 TEM-18 TEM-22 TEM-113
|
|
6.4
|
TEM-21 TEM-56 TEM-60 OXA-11
|
|
6.5
|
TEM-24 TEM-46 TEM-61
|
|
6.6
|
|
|
6.7
|
|
|
6.8
|
|
|
6.9
|
IBC-1
|
|
7
|
SHV-3 SHV-14
|
|
7.1
|
|
|
7.2
|
|
|
7.3
|
SFO-1
|
|
7.4
|
VEB-1
|
|
7.5
|
SHV-25 OXA-31 BES-1
|
|
7.6
|
SHV-2 SHV-2a SHV-6 SHV-7 SHV-8 SHV-13 SHV-19 SHV-20
|
|
7.6
|
SHV-21 SHV-26 SHV-91 OXA-19 CTX-M-8
|
|
7.7
|
|
|
7.8
|
SHV-4 SHV-18 CTX-M-44
|
|
7.9
|
CTX-M-2
|
|
8
|
OXA-13 OXA-15 OXA-35 CTX-M-9 CTX-M-18 CTX-M-19
|
|
8.1
|
OXA-28 CTX-M-10 CTX-M-14
|
|
8.2
|
SHV-5 SHV-9 SHV-10 SHV-12 SHV-22 SHV-45 SHV-90 CTX-M-13 CTX-M-16 FEC-1
|
|
8.3
|
CTX-M-20
|
|
8.4
|
CTX-M-3 CTX-M-4 CTX-M-6 CTX-M-7 CTX-M-21
|
|
8.5
|
|
|
8.6
|
CTX-M-15*
|
|
8.7
|
|
|
8.8
|
CTX-M-5
|
|
8.9
|
CTX-M-1 CTX-M-15*
|
|
9
|
CTX-M-12 TLA-1
|
* Dual pIs reported.
Page Last Modified
Thursday, November 5, 2009
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