Introduction

Rhodiola rosea is a plant that grows in the mountains of Europe and Asia. The root has been used to ease feelings of stress, anxiety, and fatigue. Rhodiola rosea can be taken as a pill, powder, or extract.

Dosages

200 milligrams twice daily

What Research Shows

May Be Effective

Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.

Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.

Safety Notes

It is likely safe to take rhodiola rosea in small doses for a short time, but it may cause lightheadedness, dry mouth, or excessive salivation. C2 Not enough studies have been done to say whether it is safe to use for a long period. It is also not known whether it is safe to take by women who are pregnant or breastfeeding.

Interactions

Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse.

References

REFA Anxiety

REFA1 Cropley M, Banks AP, et al. The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms. Phytother Res. 2015 Dec;29(12):1934-1939.

REB Depression

REFB1 Darbinyan V, Aslanyan G, et al. Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. Nord J Psychiatry. 2007;61(5):343-348.

REFB2 Dwyer AV, Whitten DL, et al. Herbal medicines, other than St. John's Wort, in the treatment of depression: a systematic review. Altern Med Rev. 2011 Mar;16(1):40-49.

REFB3 Ross SM. Rhodiola rosea (SHR-5), Part 2: A standardized extract of Rhodiola rosea is shown to be effective in the treatment of mild to moderate depression. Holist Nurs Pract. 2014;28(3):217-221.

REFB4 Mao JJ, Xie SX, et al. Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial. Phytomedicine. 2015 Mar 15;22(3):394-399.

REFC Mental Fatigue

REFC1 Olsson EM, von Schéele B, et al. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med. 2009 Feb;75(2):105-112.

REFC2 Ishaque S, Shamseer L, et al. Rhodiola rosea for physical and mental fatigue: a systematic review. BMC Complement Altern Med. 2012 May 29;12:70.

Revision Information

  • Reviewer: EBSCO NAT Review Board Eric Hurwitz, DC
  • Review Date: 07/2019
  • Update Date: 03/30/2020