• ALS Trials

    Currently, we do not have any ALS trials open to enrollment.  Trials are added on an ongoing basis. Please check back at a later date. 

    Lahey's Curt and Shonda Schilling ALS Clinic is a member of the Northeast Amyotrophic Lateral Sclerosis Consortium (NEALS).  To learn more about NEALS, upcoming or ongoing ALS clinical trials or ALS research, please visit NEALS at www.alsconsortium.org


    Ongoing ALS Clinical Trials Not Accepting New Patients or By Invitation Only 

    Title: A Multicenter Study for the Validation of ALS Biomarkers
    Principal Investigator: James Russell, DO
    Sponsor: MGH 
    Summary: This study seeks to identify factors that contribute to the pathogenesis of ALS and how discovered biomarkers change with disease course. Blood samples will be collected from ALS and suspected ALS volunteers along with patients with Motor Neuron Disease and healthy volunteers. Development of disease biomarkers and diagnostic laboratory tests would facilitate earlier treatment intervention, help monitor treatment efficacy; and, ultimately, lead to the identification of targets that could be used in therapy development.

    Title: Reliability Studies: Outcome Measures in ALS Research
    Principal Investigator: James Russell, DO
    Sponsor: NEALS
    Summary: The purpose of this protocol is to provide for uniform initial and continued reliability assessments for NEALS clinical site evaluators and to ensure their expertise in the performance of outcome measures such as: ALSRFS-R, Vital Capacity, hand-held dynamometer HHD, MUNE and Quality of Life Scales, in NEALS clinical trials. These outcome measures are used to measure multiple aspects of decline in ALS patients. Repeat certification of reliability for each site evaluator will occur every two years. 


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  • Lahey Receives Stroke Award

    The American Heart Association/American Stroke Association's Get With The Guidelines program has again awarded Lahey Clinic’s stroke service the Stroke Gold Performance Achievement Award.