• Benign Fasciculation Syndrome Trials

    Title: Natural History Study of Patients with Benign Fasciculation Syndrome 

    Study Identifier: LCID: 2010-077; BFS study 

    Principal Investigator: Doreen Ho, MD  

    Sponsor: Lahey Hospital & Medical Center

    Purpose: The purpose of this study is to further understand Benign Fasciculation Syndrome (BFS) and what factors may or may not possibly improve patient counseling and quality of life. 

    Summary: Benign Fasciculation Syndrome (BFS) is a neurological disorder characterized by fasciculation (twitching) of various voluntary muscles in the body. The twitching can occur in any voluntary muscle group but is most common in the eyelids, arms, legs, and feet. Even the tongue may be affected. The twitching may be occasional or may go on nearly continuously. Any intentional movement of the involved muscle causes the fasciculations to stop immediately, but they may return once the muscle is at rest again. BFS is usually limited to focal (one area) or widespread involuntary muscle activity (twitching).

    Studying the natural history of BFS and correlation with factors such as anxiety is essential for further understanding this disease, for counseling patients and possibly improving quality of life. 

    Study Type: Questionnaire Study 

    Length/Duration: Study participation consists of an initial office visit and 5 follow up visits to the clinic or phone contact. At each visit patients will be asked to complete a questionnaire that asks questions about their fasciculations, locations and related symptoms such as anxiety, pain and cramping and a questionnaire specific to anxiety.

    ELIGIBILITY: If you are interested in this study and would like to see if you may qualify, please complete a brief eligibility form. 

    Contact: For more information on this study, please contact the study coordinator at Jordan.Jara@lahey.org or (781) 744-2958.  



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