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by Mahnke D
(Malabsorption Syndrome)


Malabsorption is a problem getting nutrients into the body. It can happen even when someone is eating enough.

The Intestines
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There are many steps in the breakdown of food and movement of nutrients from gut to the rest of the body. The stomach and intestines need to be able to push food through the system. The stomach, liver and pancreas make fluids that help break down food. Once food is broken down, the nutrients can pass through the walls of intestine to the blood. Problems with any part of this process can cause malabsorption.

Risk Factors

The risk of malabsorption is higher in people with:

  • Problems of liver or pancreas
  • Difficulty moving food in the intestines
  • Crohn disease, celiac disease, parasite infection, or other disease of intestines
  • Laxative use
  • Antibiotic use
  • Prior surgery on the intestines
  • Alcohol use disorder


Malabsorption may cause:

  • Weight loss
  • Bloating and swelling in the belly
  • Diarrhea
  • Bulky, foul-smelling stools
  • Weak muscles
  • Tiredness


You will be asked about your symptoms and past health. A physical exam will be done. The doctor may suspect malabsorption based on what is told to them. Blood tests may help to show imbalances in some nutrients. Other tests may be done to look for a cause.


Treatment will be based on the cause. Treating the cause may stop malabsorption.

Special food or supplements may be needed to improve nutrition. Some vitamins, minerals, fats, or proteins may need to be increased. It may be needed if the cause cannot be fully treated or until the cause is managed. Nutrients may also be given by IV.


Steps to prevent malabsorption will depends on the cause.


American College of Gastroenterology  http://patients.gi.org 

NORD—National Organization for Rare Disorders  https://rarediseases.org 


Canadian Association of Gastroenterology  https://www.cag-acg.org 

Health Canada  https://www.canada.ca 


Abdullah M, Firmansyah MA. Clinical approach and management of chronic diarrhea. Acta Med Indones. 2013;45(2):157-165.

Bacterial overgrowth syndrome. Merck Manual Professional Version website. Available at: http://www.merckmanuals.com/professional/gastrointestinal%5Fdisorders/malabsorption%5Fsyndromes/bacterial%5Fovergrowth%5Fsyndrome.html. Updated February 2018. Accessed August 13, 2018.

Chronic diarrhea. EBSCO DynaMed Plus website. Available at:  https://www.dynamed.com/topics/dmp~AN~T114891/Chronic-diarrhea  . Updated July 1, 2016. Accessed August 13, 2018.

Diarrheal diseases—acute and chronic. American College of Gastroenterology website. Available at: http://patients.gi.org/topics/diarrhea-acute-and-chronic. Updated December 2012. Accessed August 13, 2018.

Overview of malabsorption. Merck Manual Professional Version website. Available at: https://www.merckmanuals.com/professional/gastrointestinal-disorders/malabsorption-syndromes/overview-of-malabsorption. Updated February 2018. Accessed August 13, 2018.

Revision Information

  • Reviewer: EBSCO Medical Review Board Daus Mahnke, MD
  • Review Date: 05/2018
  • Update Date: 01/16/2020