by EBSCO Medical Review Board


Raynaud phenomenon is a problem with the blood vessels. It leads to blood flow problems in the fingers, ears, nose, and lips. It may be:

  • Primary—not linked to another health problem (common form)
  • Secondary—linked to another health problem, such as systemic sclerosis, joint disease, blood disorder, or blocked arteries


Blood vessels narrow when a person is cold or under stress. In Raynaud, the blood vessels narrow too much. This leads to poor blood flow to nearby tissue. Fingers are often affected.

The exact cause of primary Raynaud is not known. Secondary Raynaud is caused by the linked disease.

Risk Factors

This problem is more common in woman. Other things that may raise the risk are:

  • Repeated activity or stress to the hands, such as:
    • Typing
    • Playing piano
    • Using vibrating tools, as in construction
    • Exposure to certain chemicals
  • Connective tissue disease, such as scleroderma
  • Diseases of the arteries, such as atherosclerosis
  • Injury of the hands or feet, such as wrist fractures or frostbite
  • Smoking
  • Certain medicines, such as:
    • Beta-blockers
    • Cancer chemotherapy
    • Cold medicine
    • Migraine medicine that has ergotamine
    • Estrogen-containing medicine


Symptoms appear in attacks. They are most common in cold weather and when a person is under stress. Problems may last a few minutes to a few hours.

During an attack, problems may be:

  • A change in skin color to white then to blue when blood flow is slowed
  • Skin color change to red once blood is flowing again
  • Throbbing and tingling, stinging, pain, and swelling of the area when blood flow returns
Constriction of Blood Vessels
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The doctor will ask about your symptoms and health history. A physical exam will be done. This is often enough to make the diagnosis. Other tests may be done to look for a cause.


There is no cure. The goal of treatment is to lower the number of attacks and decrease how severe they are. Treating any related health problem will help to manage secondary Raynaud.

Options are:

  • Identifying triggers and taking steps to avoid them.
  • Avoid or quit smoking.
  • Exercising regularly.
  • Medicine to improve blood flow, such as:
    • Calcium channel blockers
    • Alpha-blockers
    • Vasodilators

Nerves control the size of blood vessels. Procedures to destroy or stop the nerves may be needed if other steps have not worked. The nerves may be stopped with:

  • Chemical injection—chemical stops the nerves from working
  • Surgery—nerves are cut (rare)


There are no known guidelines to prevent this health problem.


Arthritis Foundation 

National Heart, Lung, and Blood Institute 


The Arthritis Society 

Heart and Stroke Foundation of Canada 


Herrick AL. Evidence-based management of Raynaud’s phenomenon. Ther Adv Musculoskeletal Dis. 2017;9(12):317-329.

Raynaud's. National Heart, Lung, and Blood Institute website. Available at: Accessed July 21, 2021.

Raynaud phenomenon. EBSCO DynaMed website. Available at: Accessed July 21, 2021.

Revision Information

  • Reviewer: EBSCO Medical Review Board Rimas Lukas, MD
  • Review Date: 07/2021
  • Update Date: 07/21/2021