Introduction
Perilla frutescens is an herb in the mint family. The leaves and seeds have been used to slow damage to cells. Perilla frutescens has also been used to help digestion and ease allergy symptoms. It can be taken as a pill, powder, or extract. Perilla frutescens can also be used as an oil or made into a tea.
Dosages
There are no advised doses for perilla frutescens
What Research Shows
May Be Effective
- Allergic rhinitis—may ease symptoms A1
Not Enough Data to Assess
Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.
Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.
Safety Notes
It is likely safe to take perilla frutescens in small doses for a short time, but allergic reaction may happen in some people. D1 Not enough studies have been done to say whether it is safe to use for a long period. It is also not known whether it is safe to take by women who are pregnant or breastfeeding.
Interactions
Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse.
References
REFA Allergic Rhinitis
REFA1 Guo R, Pittler MH, et al. Herbal medicines for the treatment of allergic rhinitis: a systematic review. Ann Allergy Asthma Immunol. 2007 Dec;99(6):483-495.
REFB Allergic Rhinoconjunctivitis
REFB1 Takano H, Osakabe N, et al. Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans. Exp Biol Med (Maywood). 2004 Mar;229(3):247-254.
REFC Gastrointestinal Pain
REFC1 Buchwald-Werner S, Fuji H, et al. Perilla extract improves gastrointestinal discomfort in a randomized placebo controlled double blind human pilot study. BMC Complement Altern Med. 2014;14:173.
REFD Safety
REFD1 Yu H, Qiu JF, et al. Phytochemical and phytopharmacological review of Perilla frutescens L. (Labiatae), a traditional edible-medicinal herb in China. Food Chem Toxicol. 2017 Oct;108(Pt B):375-391.