Supplement Forms/Alternate Names:
- Opuntia, prickly pear cactus, jumping prickly-pear cactus, tree cactus
Introduction
Nopal is a cactus that is used when cooking. It has been used to control blood glucose and body mass index (BMI). Nopal can be cooked then eaten or taken as a syrup. It can also be taken as a pill, powder, or extract. Nopal can also be made into a tea.
Dosages
There aren’t any advised doses for nopal.
What Research Shows
May Be Effective
- Diabetes —may lower blood glucose B1-B3
- Metabolic syndrome —may ease symptoms C1
Not Enough Data to Assess
Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.
Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.
Safety Notes
It is likely safe to take nopal in small doses for a short time, but it may cause nausea, changes in bowel movements, and headache. E1-E3 Not enough studies have been done to say whether it is safe to use for a long period. It is not known whether nopal is safe to take by women who are pregnant or breastfeeding.
Interactions
Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse.
References
REFA Alcohol Hangover
REFA1 Wiese J, McPherson S, et al. Effect of Opuntia ficus indica on symptoms of the alcohol hangover. Arch Intern Med. 2004 Jun 28;164(12):1334-1340.
REFA2 Pittler MH, Verster JC, et al. Interventions for preventing or treating alcohol hangover: systematic review of randomised controlled trials. BMJ. 2005 Dec 24;331(7531):1515-1518.
REFB Diabetes
REFB1 Rodriguez-Fragoso L, Reyes-Esparza J, et al. Risks and benefits of commonly used herbal medicines in Mexico. Toxicol Appl Pharmacol. 2008 Feb 15;227(1):125-135.
REFB2 Godard MP, Ewing BA, et al. Acute blood glucose lowering effects and long-term safety of OpunDia supplementation in pre-diabetic males and females. J Ethnopharmacol. 2010 Aug 9;130(3):631-634.
REFB3 López-Romero P, Pichardo-Ontiveros E, et al. The effect of nopal (Opuntia ficus indica) on postprandial blood glucose, incretins, and antioxidant activity in Mexican patients with type 2 diabetes after consumption of two different composition breakfasts. J Acad Nutr Diet. 2014 Nov;114(11):1811-1818.
REFC Metabolic Syndrome
REFC1 Linarès E, Thimonier C, et al. The effect of NeOpuntia on blood lipid parameters--risk factors for the metabolic syndrome (syndrome X). Adv Ther. 2007 Sep-Oct;24(5):1115-1125.
REFD Obesity
REFD1 Grube B, Chong PW, et al. A natural fiber complex reduces body weight in the overweight and obese: a double-blind, randomized, placebo-controlled study. Obesity (Silver Spring). 2013 Jan;21(1):58-64.
REFD2 Onakpoya IJ, O’Sullivan J, et al. The effect of cactus pear (Opuntia ficus-indica) on body weight and cardiovascular risk factors: a systematic review and meta-analysis of randomized clinical trials. Nutrition. 2015;31(5)640-646.
REFE Safety
REFE1 Rodriguez-Fragoso L, Reyes-Esparza J, Burchiel SW, Herrera-Ruiz D, Torres E. Risks and benefits of commonly used herbal medicines in Mexico. Toxicol Appl Pharmacol. 2008 Feb 15;227(1):125-135.
REFE2 Sobieraj DM, Freyer CW. Probable hypoglycemic adverse drug reaction associated with prickly pear cactus, glipizide, and metformin in a patient with type 2 diabetes mellitus. Ann Pharmacother. 2010 Jul-Aug;44(7-8):1334-1337.
REFE3 Izzo AA. Interactions between herbs and conventional drugs: overview of the clinical data. Med Princ Pract. 2012;21(5):404-428.